First Zipper-Featured Molecular Duplexes Driven by Cooperative Donor−Acceptor Interaction
نویسندگان
چکیده
منابع مشابه
A Molecular “Zipper” for Microtubules
The dynamics of the microtubule cytoskeleton are controlled by microtubule-associated proteins (MAPs). In this issue, show that Mal3p, the yeast EB1 homolog, belongs to a new class of MAPs that "zipper" up the seam of the microtubule lattice.
متن کاملElastically driven cooperative response of a molecular material impacted by a laser pulse.
Photoinduced phase transformations occur when a laser pulse impacts a material, thereby transforming its electronic and/or structural orders, consequently affecting the functionalities. The transient nature of photoinduced states has thus far severely limited the scope of applications. It is of paramount importance to explore whether structural feedback during the solid deformation has the capa...
متن کاملCoiled-coil driven membrane fusion: zipper-like vs. non-zipper-like peptide orientation.
Membrane fusion plays a central role in biological processes such as neurotransmission and exocytosis. An important class of proteins that induce membrane fusion are called SNARE (soluble N-ethyl malemeide sensitive factor attachment protein receptors) proteins. To induce membrane fusion, two SNARE proteins embedded in opposing membranes form a four-helix coiled-coil motif together with a third...
متن کاملIdentification of BKCa channel openers by molecular field alignment and patent data-driven analysis
In this work, we present the first comprehensive molecular field analysis of patent structures on how the chemical structure of drugs impacts the biological binding. This task was formulated as searching for drug structures to reveal shared effects of substitutions across a common scaffold and the chemical features that may be responsible. We used the SureChEMBL patent database, which prov...
متن کاملNovelty-Driven Cooperative Coevolution
Cooperative coevolutionary algorithms (CCEAs) rely on multiple coevolving populations for the evolution of solutions composed of coadapted components. CCEAs enable, for instance, the evolution of cooperative multiagent systems composed of heterogeneous agents, where each agent is modelled as a component of the solution. Previous works have, however, shown that CCEAs are biased toward stability:...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Organic Letters
سال: 2003
ISSN: 1523-7060,1523-7052
DOI: 10.1021/ol030076a